Non surgical treatment of chronic anal fissure: one year`s experience with GTN paste

Authors

  • Rizwan Aziz
  • Faridud Din
  • Muhammad Shoaib
  • Muhammad Kamran

DOI:

https://doi.org/10.21649/akemu.v11i4.1063

Keywords:

Fissure in Ano. Glyceryl Trinitrate. Administration, Topical. Vasodilator Agents. Anal Canal. Dosage Forms. Ointments. Emollients. Manometry.

Abstract

Objective: Assessment of the efficacy of topical 0.2% glyceryl trinitrate (GTN) paste in the treatment of chronic anal fissure. Patients and Methods: Sixty two patients were treated with 0.2% GTN paste and reviewed at 3, 6 and 12 weeks interval to assess efficacy and side effects. Results: At 6 weeks, 72% of patients were treated successfully. In 28% of cases treatment was unsuccessful. At 12weeks follow up there was no early recurrence. The prevalence of headaches was 70%. Conclusions: The use of GTN induces rapid healing of chronic anal fissures with a 72% healing rate in this study. But balance is required between fissure healing and headache intolerance.

Published

2016-04-21

How to Cite

Aziz, R., Din, F., Shoaib, M., & Kamran, M. (2016). Non surgical treatment of chronic anal fissure: one year`s experience with GTN paste. Annals of King Edward Medical University, 11(4). https://doi.org/10.21649/akemu.v11i4.1063

Issue

Section

Articles