Incidence of malignant Obstructive Jaundice - a study of hundred patients at Nishtar Hospital Multan

Abstract

The objective of this study is to see the incidence of malignant obstructive jaundice. It is a descriptive study carried out at. Nishtar Hospital Multan from January 2000 to January 2002. Total 100 patients with obstructive jaundice were included in study. The patients with benign diseases were excluded. The patients having malignant obstructive jaundice were studied in detail and incidence of malignant obstructive jaundice was noted. The main presenting symptoms were progressive painless jaundice, pruritis, anorexia, weight loss, abdominal pain and mass right upper abdomen. 84 patients (84%) were suffering from malignancy and 16 patients (16%) were suffering from benign diseases. The incidence of various malignancies was CA gall bladder 44 patients (52%), CA Pancreas 26 patients (31%), Cholangiocarcinoma 8(10%) and Hepatoma 6 patients (7%). Incidence of malignancy in obstructive jaundice is 84%, which gradually increases with the increasing age. The most common malignancy responsible for obstructive jaundice in female patients is CA gall bladder (52%) and in male patients is CA head of pancreas (31%).