Frequency of Hypercholesterolemia in Recent Onset Type – 2 Diabetics with Microalbuminuria

Abstract

Abstract

Amongst diabetes, type 2 diabetes encompasses more than 80% and even higher percentage is present in un-industrialized countries. Kidney disease in diabetic patients is clinically characterized by increasing rates of urinary albumin excretion, starting from no albuminuria, which progresses to microalbuminuria, macro-albuminuria and eventually to End Stage Renal Disease. Dyslipidemia is observed in patients with DM and microalbuminuria. Total cholesterol increases significantly with albuminuria.

Objectives:  Frequency of hypercholesterolemia in recent onset type-2 diabetics with microalbuminuria.

Methodology:  The study was conducted in Department of Endocrinology & Metabolism, Services Hospital Lahore. Study was conducted and completed over a period of six months from 15^th September 2014 to 15^th March 2015. It was a cross sectional survey with non-probability, purposive sampling technique. 200 patients fulfilling the criteria were enrolled. Informed consent was obtained. Demographic information of each patient was noted. Urine was obtained and samples were sent to the laboratory of the hospital and reports were assessed. If the value of albumin is raised in urine analysis (as per operational definition) then albuminuria was labeled. In patients who were diagnosed as with albuminuria, total cholesterol was noted. If cholesterol was > 240 mg/dl, then hypercholesterolemia was labeled by researcher himself.

Conclusion:  The results of the study conclude that frequency of microalbuminuria among patients of newly diagnosed type-2 diabetic mellitus is in agreement with other studies while the frequency of hyper-cholesterolemia in patients with microalbuminuria was also recorded higher which needs special physicians attention for its timely management so that patients can be prevented from severe cardio vascular morbidi-ties and mortality.