Presentation and Etiological Factors of Cancer Gall Bladder in Patients undergoing Cholecystectomies at Mayo Hospital, Lahore.

Abstract

Carcinoma of the gall bladder is a progressive malignant disorder with a poor and painful prognosis and a high mortality rate’. Our report highlights the enhanced presentation of the carcinoma of gallbladder in Patients having cholecystectomy in a general surgical ward, and its possible etiological factors in the population of Pakistan in general and Punjab in particular. This is a retrospective non analytical study in which case records and histopathology reports of loo patients who underwent cholecystectomy was studied, with the objective to determine the incidence of cancer of gall bladder and highlight the possible etiological factors. 89% of the study group were females and 11% males. Cancer of gall bladder among the 100 patients was 12%; the highest yet reported  in literature and it was seen that it was more common ¡n females (10%) who are relatively quite young in age. The etiological factors held responsible were the unmistakable association of gall stones, the delayed treatment, repeated attacks of choiecystitis, multi parity, congenital abnormalities of biliary tract infections of the biliary system, Polyps of the Gall Bladder and Mirrizi syndrome, the incidence of the Gall Bladder cancer is very high in our population. A number of possible etiological factors have been highlighted and the bulk of them can be prevented. or controlled.