PUVA Therapy for Psoriasis
AbstractTwenty three patients of psoriasis were treated with thrice weekly PUVA therapy. Complete clearing of the disease was seen in 20/23 patients (87%). On the average, a patient required 25 exposures, cumulative dose of 137 J/cm2 and 8.5 weeks for clearance. The treatment was discontinued in three patients due to worsening of the disease. After clearing of the disease, 18 patients (90%) received maintenance therapy, which was then tapered off. Only 8 patients relapsed after 6 months of stoppage of the treatment. The most common side effect noted was nausea (30%), followed by pruritus (23%), erythema (13%), headache (7%), Koebner’s phenomenon (5%) and blister formation (4%).
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