Clinico-Pathological Features of Soft Tissue Sarcoma (STS)

Abstract

The object of the study was to review the Clinico-pathological features of soft tissue sarcoma. The data of 86 patients, who were treated at Clinical Oncology Department Mayo Hospital Lahore, was collected from medical record for the year 1997-98 and analyzed for various parameters. The hospital frequency was 3.51 % of all the malignancies with male to female ratio 1.2:1. Maximum patients were aged between 16-45 years. Two cases had genetically determined neurofibromatosis. Major histopathology noted was Fibro sarcoma (20.93%) followed by Rhabdomyosarcoma and Malignant fibrous histiocytoma 16.28% and 13.95% respectively. In patients with distant metastasis lung was the most common site involved. Lower limb and head & neck were predominantly involved sites 46.51% and 16.28% respectively. Children were having mostly Rhabdomyosarcoma, young adults had Fibrosarcoma and older ones presented with Malignant Fibrous Histiocytoma. Males were having predominantly Fibrosarcoma and females Liposarcomas. It was concluded that frequency of soft tissue sarcoma in our set up is little higher and middle aged patients were affected more. Commonest histopathology was Fibrosarcoma instead of Malignant Fibrous Histiocytoma. Head and neck was second common site involved in our study. The majority of patients presented late which needs mass education about the disease detection.