Efficacy of the Intravitreal Bevicizumab in the Treatment of Vitreous Hemorrhage in Proliferative Diabetic Retinopathy

Abstract

Purpose:  To determine the efficacy of bevicizumab in the treatment of vitreous hemorrhage in proliferative diabetic retinopathy.

Material and Method:  The hundred patients with type I and type II diabetes mellitus for more than 7 to 8 years and having New vessels at the disc (NVD) or elsewhere on the fundus (NVE) were collected from Mayo hospital outpatient department. After taking in-formed consent and recording the demographic details including name, age, sex, address etc patients were admitted in ward of Eye unit I for injection bevicizu-mab (Avestin). Patients were evaluated and graded by directly taking the fundus picture and B-scan. Patients were examinned second week and finally on the fourth week by again directly taking the fundus photograph and doing the B – scan for assessing the efficacy of bevicizumab.

Results:  Intravitreal Avastin reduced the vitreous hemorrhage in 39% of patients while in 61% of pati-ents it was not successful in suppressing the vitreous hemorrhage.

Conclusion:  Intravitreal Avastin reduced the chance of the vitreous hemorrhage and hence improved the vision and significantly prevented the patients from the massive surgical procedure of vitrectomy.