Comparison of Osteoclast Count and Amount of Orthodontic Tooth Movement in Flap Corticotomy and Flapless Bur Decortication: A Preclinical Study on Rats
Keywords:Osteoclast, tooth movement techniques, orthodontic appliance, rats, Sprague-Dawley.
AbstractBackground: Flapless bur decortication is a minimally invasive approach that can be performed as an adjunct to orthodontic treatment to expedite tooth movement. Objective: The aim of our study was to compare amount of orthodontic tooth movement and osteoclast count in flap corticotomy and flapless bur decortication using 20 cN force in rats. Methodology: The study was performed at animal house, Postgraduate Medical Institute, Lahore after ethical approval from institutional review board. A total of 36 male, 10-12 weeks old, (200±20 gm) Sprague-Dawley rats were randomly divided in three groups: (1) appliance only (control, n = 12), (2) flap corticotomy (FC) with appliance (n = 12), (3) flapless bur decortication (FLBD) with appliance (n = 12). Rats were euthanized at 14 days. Initial and final tooth movement were recorded using digital caliper. Osteoclast count was performed using hematoxylin-and-eosin staining method. Results: The amount of orthodontic tooth movement and osteoclast count were significantly higher in flap corticotomy and flapless bur decortication groups than control (P < 0.05). However, no significant differences were found in mean tooth movement (P = 0.99) and mean osteoclast count (P=0.98) between flap corticotomy and flapless bur decortication. Conclusion: Within the limit of current study, flap corticotomy and flapless bur decortication did not show a significant difference in the amount of orthodontic tooth movement and osteoclast which suggest that flapless bur decortication can be used to accelerate tooth movement.
How to Cite
This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For comments email@example.com