DISSEMINATED CYTOMEGALOVIRUS INFECTION IN AN IMMUNOCOMPETENT ADOLESCENT: A CASE REPORT

Abstract

Abstract

CMV (Cytomegalovirus) is ubiquitous. In humans most CMV infections are asymptomatic. After primary infections, virus remains latent in most body cells and can be isolated from a variety of tissues under non pathological conditions. Mostly CMV dissemination was considered a feature of immunosupressed state however serious life threatening disseminated infect-ions are also manifested in immunocompetent patients as is highlighted in this case report. Literature review showed that serious infections with CMV in immuno-competent individuals are not as rare as were previo-usly thought and can be as devastating as is depicted in this scenario leading to sudden bilateral hearing and visual loss. In our study immunosupression was ruled out by absence of Diabetes Mellitus, chronic kidney disease, immunodeficiency disorders (congenital and acquired), hematological and non-haematological malignancies, treatment with steroids or immuno-modulator / immunosupressant agents and organ trans-plantation.

Key Words:  Disseminated CMV Infection, Immuno-competent individual, Serial Antibody Serologies, Dia-gnostic and Therapeutic limitations.