@article{Khan_Hameed_Umber_2011, title={Histopathological Pattern of Endometrium on Diagnostic D & C in Patients with Abnormal Uterine Bleeding}, volume={17}, url={https://annalskemu.org/journal/index.php/annals/article/view/293}, DOI={10.21649/akemu.v17i2.293}, abstractNote={<p><strong>Aims and Objectives:</strong>  To determine histopathologi-cal pattern of endometrium in patients with abnormal uterine bleeding.</p> <p><strong>Study Type:</strong>  Observational, Cross sectional.</p> <p><strong>Place of Study:  </strong>Obs and Gynae department, Madina teaching hospital, FSD.</p> <p><strong>Duration of Study:  </strong>One and a half year from Oct 2008 to Apr 2010.</p> <p><strong>Patients and Methods:</strong>  Patients presenting to Madina teaching hospital OPD with complaint of abnormal uterine bleeding were assessed via inclusion and ex-clusion criteria to be included in this study. A detailed history was followed by general physical, systemic, and gynecological examination. A pelvic ultrasound was performed followed by diagnostic D&C. Endo-metrial biopsy sent for histopathological examination in Pathology department of Madina teaching hospital, FSD. Data was collected over a period of one and a half year, and shifted to computer for analysis. Statisti-cal package of social sciences (SPSS) version 15 was used for statistical analysis of data. Chi-square good-ness of fit was used as test of statistical significance.</p> <p><strong>Results:  </strong>The most common pathological pattern iden-tified was proliferative phase endometrium (46.4%). Secretary phase endometrium was second most common pathology (37.6%). Cystic (5.2%), adenomatous (3.8%), and atypical (3.6%) hyperplasia constituted 12.6% of bulk. In 1.4%, endometritis was identified as a cause of abnormal uterine bleeding followed by atrophic endometrium (1%). Polyp was identified in 0.6% of cases followed by endometrial carcinoma (0.4%).</p> <p><strong>Conclusion:  </strong>Histopathological pattern of endomet-rium in patients with abnormal uterine bleeding is qui-te variable regardless of age, parity and ethnicity. Al-though the incidence of endometrial hyperplasia is grossly variable, yet incidence of endometrial carci-noma is small in all sited studies.</p> <p><strong>Key words:</strong>  D&C, AUB.</p> <p> </p>}, number={2}, journal={Annals of King Edward Medical University}, author={Khan, Sadia and Hameed, Sadia and Umber, Aneela}, year={2011}, month={Sep.}, pages={166} }