@article{Ahmed_Shaheer_Ch._Tahir_Nadeem_Yousaf_Malik_Rehman_2015, title={ROLE OF AVASTIN ON THE INCIDENCE OF POST OPERATIVE VITREOUS HEMORRHAGE AFTER VITREC-TOMY IN DIABETIC VITREOUS HEMORRHAGE}, volume={20}, url={https://annalskemu.org/journal/index.php/annals/article/view/671}, DOI={10.21649/akemu.v20i3.671}, abstractNote={<p><strong>Abstract</strong></p> <p>Diabetic retinopathy is one of the most common cause of legal blindness. Five to 10% of diabetic patients suffer from the proliferative diabetic retinopathy whi-ch includes the formation of new vessels on the retina</p> <p>Ahmed N.<sup>1</sup></p> <p>Consultant Eye Surgeon, Vitreo Retina Fellow Eye Unit - III, KEMU / Mayo Hospital, Lahore</p> <p>Shaheer M.<sup>2</sup></p> <p>Medical Officer, Eye Unit - III, Mayo Hospital, Lahore</p> <p>Latif Q.<sup>3</sup></p> <p>Associate Professor, Jinnah Hospital, Lahore</p> <p>Tahir M.Y.<sup>4</sup></p> <p>Associate Professor, Quaid-e-Azam Medical College, Bahawalpur</p> <p>Nadeem H.M.<sup>5</sup></p> <p>Consultant Vitreo Retina, Nishtar Hospital, Multan</p> <p>Yousaf A.<sup>6</sup></p> <p>Medical Officer, Eye Unit-III, Mayo Hospital, Lahore</p> <p>Malik H.A.<sup>7</sup></p> <p>MBBS Final Year, PMC, Faisalabad</p> <p>Rehman M.U.<sup>8</sup></p> <p>Medical Officer, Eye Unit - III, Mayo Hospital, Lahore</p> <p>and optic disc which can be complicated as vitreous hemorrhage and tractional retinal detachment. Pars plana vitrectomy along with laser photocoagulation is being used for the management of vitreous hemorr-hage. In our study we used injection avastin one week before surgery to see its role on the incidence of re-bleed after vitrectomy in diabetic vitreous hemorrhage.</p> <p><strong>Materials and Methods:  </strong>Fifty patients were divided into 2 equal groups on the basis of simple random sampling. 25 patients in Group I were operated with routine pars plana vitrectomy with endolaser photo-coagulation while in Group II all the 25 patients were given injection avastin intra-vitreally one week before surgery. Evaluation was done on the first post opera-tive day, first follow up visit (one week) and after one month to see the incidence of re-bleed. Chi-square test was used for statistical analysis.</p> <p><strong>Results:  </strong>Fifty patients divided into two groups. In Group I, 3 patients had recurrent vitreous hemorrhage on first post-operative day, 3 patients had re-bleed on first follow up visit, and only 2 patients had re-bleed after one month. In Group II, none of the patients had recurrent vitreous hemorrhage on first post-operative day and on first follow-up visit (one week) while 2 patients had re-bleed after one month.</p> <p><strong>Conclusion:  </strong>Injection intravitreal Avastin (Bevaci-zumab) one week before surgery significantly reduces the risk of vitreous hemorrhage after vitrectomy in dia-betic patients.</p><p><strong>Keywords:  </strong>Avastin, bevacizumab, re-bleed, recurrent vitreous hemorrhage, diabetes, proliferative diabetic retinopathy.</p>}, number={3}, journal={Annals of King Edward Medical University}, author={Ahmed, Nasir and Shaheer, Muhammad and Ch., Qasim Latif and Tahir, Muhammad Younis and Nadeem, Hafiz Muhammad and Yousaf, Ateeq and Malik, Hashir Amin and Rehman, Munib-ur-}, year={2015}, month={Aug.}, pages={252} }