@article{Zaidi_Ahmad_Mehboob_2015, title={VARIATION IN REGIONAL DISTRIBUTION OF MULTIPLE SCLEROSIS PLAQUES IN PAKISTANI AND CANADADIAN NATION}, volume={20}, url={https://annalskemu.org/journal/index.php/annals/article/view/684}, DOI={10.21649/akemu.v20i4.684}, abstractNote={<p><strong>Abstract</strong></p> <p><strong>Background and Purpose:</strong>  To determine retrospec-tively the variation in regional involvement of brain among established cases of MS Canadian and Pakis-tani nation. We also analyzed parahippocampal gyrus lesions with further characterization according to grey white matter distribution.</p> <p><strong>Methods:</strong>  Sixty patients presenting clinically with multiple sclerosis were included as two groups of thir-ty each from Canadian and Pakistani nation respect-tively. Imaging was performed on 1.5 T MR system acquiring T<sub>1</sub>W, T<sub>2</sub>W, Proton density, FLAIR and T<sub>1</sub>W post gadolinium sequences. Lesions were counted and classified according to anatomic regions paraventri-cular, temporal lobe and juxtacortical. The juxtacorti-cal involvement of parahippocampal region consider-ing brain parenchymal involvement were classified.</p> <p>Zaidi N.R.<sup>1</sup></p> <p>Former Professor of Radiology</p> <p>KEMU / Mayo Hospital, Lahore</p> <p>Ahmad M.W.<sup>2</sup></p> <p>Medical Officer</p> <p>Department of Radiology, Mayo Hospital, Lahore</p> <p>Mehboob R.<sup>3</sup></p> <p>Assistant Professor Department of Pathology</p> <p>King Edward Medical University, Lahore</p> <p><strong>Results:</strong>  Canadians haved more disease load as com-pare to Pakistani nation. Mean age of the patients are relatively younger in Canadians however anatomical lesional distribution in temporal lobe, paraventricular and parahippocampal region more or less same.</p> <p><strong>Conclusion:</strong>  Multiple sclerosis is more common amo-ng Canadian however its lesional anatomical distri-bution including parahippocampal region had no sig-nificant variation.</p> <p><strong>Keywords:</strong>  Multiple sclerosis (MS), Periventricular (PVC), Temporal lobe, Juxtacortical (JC) and Para-hippocampal.</p> <p> </p>}, number={4}, journal={Annals of King Edward Medical University}, author={Zaidi, Nasir Raza and Ahmad, Mian Waheed and Mehboob, Riffat}, year={2015}, month={Aug.}, pages={340} }