Coagulation profile in male albino rats fed on Nigella sativa and aspirin for six weeks duration

Ghazanfar Ali Sirhindi; Shahida Amjad Riaz Shah; Muhammad Javed Asif; Mateen Izhar

doi:10.21649/akemu.v10i4.1252

Coagulation profile in male albino rats fed on Nigella sativa and aspirin for six weeks duration

Authors

Ghazanfar Ali Sirhindi
Shahida Amjad Riaz Shah
Muhammad Javed Asif
Mateen Izhar

DOI:

https://doi.org/10.21649/akemu.v10i4.1252

Keywords:

Nigella sativa. Lecithin Acyltransferase Deficiency. Blood Coagulation Tests. Diets. Aspirin. Plant Preparations. Plant Oils. Triglycerides. Aspartate Aminotransferases.

Abstract

In this study ninety male albino rats were selected and were divided into six groups on the basis of different diets given. Control group (I) was fed on synthetic diet and experimental groups (IIA, IIB, IIC, IID and IIE) were fed on I mg aspirin, 15 mg, 30 mg, 45 mg Nigella sativa per kg body weight respectively while HE was given 30 mg Nigella sativa and I mg aspirin/kg body weight. Blood samples were collected by heart puncture and coagulation parameters were done. BT was prolonged in groups taking aspirin only. APTT was reduced significantly in groups taking different concentrations of Nigella sativa when compared with the control. Percentage of clot retraction was weak significantly in groups taking aspirin only when compared with other groups of male albino rats.

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Published

05/17/2016

How to Cite

Sirhindi, G. A., Riaz Shah, S. A., Asif, M. J., & Izhar, M. (2016). Coagulation profile in male albino rats fed on Nigella sativa and aspirin for six weeks duration. Annals of King Edward Medical University, 10(4). https://doi.org/10.21649/akemu.v10i4.1252

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Issue

Vol. 10 No. 4 (2004): AKEMU

Section

Research Articles

License

This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For comments publications@kemu.edu.pk

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Coagulation profile in male albino rats fed on Nigella sativa and aspirin for six weeks duration