Gastric Fluid Volume & pH: A Comparison of Effects of Ranitidine Alone with Combination of Ranitidine and Metoclopramide in Patients Undergoing Elective Caesarean Section.
Keywords:Aspiration pneumonitis, gastric fluid volume, gastric fluid pH, elective caesarean section
Seventy five patients undergoing elective caesarean section under general anaesthesia were randomly divided into three groups of twenty five patients each to receive placebo (group 1), H-2 receptor blocker, ranitidine (group 11) and combination of II-2 receptor blocker and prokinetic drug, metoclopramide (group III). Gastric fluid volume >25 ml was recorded in sixteen (64%) patients in-group I, in three (12%) patients in-group II and in six (24%) patients in-group UT. Gastric fluid pH <25 was recorded in sixteen (64%) patients in group I, in one (4%) patient in group II and no patient in group III Group II and UI patients were not statistically significantly different (p-value <0.05) regarding both the parameters but group I patients were at a high risk (60%) of aspiration pneumonitis when compared to group II and III (p-value >0.05).
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