Diabetes Mellitus Among Patients with Cirrhosis Due to Hepatitis C Virus and its Association with Hepatic Encephalopathy

Authors

  • Muhammad Kamran Yousaf
  • Shazia Nourin
  • Amjad Khan
  • Muhammad Irfan Yousaf
  • Sajid Abaid Ullah
  • Sidrah Lodhi

DOI:

https://doi.org/10.21649/akemu.v26i1.3298

Keywords:

Hepatic encephalopathy (HE), Neuropsychometric Test, West Heaven Criteria, Hepatitis C Virus(HCV), Diabetes Mellitus(DM)

Abstract

Background: Diabetes Mellitus (DM) is frequent in chronic liver disease and there is an increased association of DM with Hepatitis C andhepatic encephalopathy (HE). In our setup such studies are not published and we do not have the updated knowledge of the above mentioned phenomena. Objectives: To determine the frequency of DM in HCV cirrhotic patients and association of HE in HCV Cirrhotic patients with DM Materials And Methods: This Analytical cross-sectional study was conducted in Medicine Department, Mayo hospital, Lahore.100 patients with HCV associated cirrhosis were included using non-probability purposive sampling. Patients were stratified as diabetic and non-diabetic according to ADA criteria and presence of HE was determined clinically. Frequency and percentage of HE & diabetes were calculated and odds ratio was calculated to determine association. P-value <0.05 was considered significant. Results: The mean age of patients was 44.43±10.16 years and there were 66% males and 34% females. 34% among HCV cirrhosis patients were diabetic. HE was seen in 31(91.2%) of the diabetic patients and in 48(72.7%) of non-diabetic patients with odds ratio of 3.875 (p-value 0.016) Conclusion: There is a significant association between diabetes mellitus and HE among patients with HCV associated cirrhosis.

Published

2020-06-04

How to Cite

Yousaf, M. K. ., Nourin, S. ., Khan, A. ., Yousaf, M. I. ., Ullah, S. A. ., & Lodhi, S. . (2020). Diabetes Mellitus Among Patients with Cirrhosis Due to Hepatitis C Virus and its Association with Hepatic Encephalopathy. Annals of King Edward Medical University, 26(1), 36-40. https://doi.org/10.21649/akemu.v26i1.3298

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