Haemophilia A (Factor VIII: C deficiency) A clinicohaematological Study of 20 Cases
Keywords:Haemophilia A, blood coagulation, factor VII.
AbstractHereditary disorders of blood coagulation are 2nd common congenital disorders. Haemophilia A is the most frequently encountered serious disorder of coagulation, if not properly diagnosed and managed, can lead to severe disability in the male child of the family and at times can be life threatening also. Present clinicohaematological study was carried out on 20 cases of haemophilia A at the Pathology Deptt. of King Edward Medical College, Lahore. Coagulation study and factor VIII assays were carried out and severity of the disease determined. In our study 5 (25%) of the cases had severe deficiency, 5 (25%) moderate deficiency and 10 (50%) of cases were of mild factor VIII deficiency. The clinical presentations correlated with level of factor VIII in the plasma.
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