Pregnancy Outcome in Acute Viral Hepatitis E

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Pregnancy Outcome in Acute Viral Hepatitis E

DOI:

https://doi.org/10.21649/akemu.v28i1.5006

Keywords:

Acute hepatitis, feto-maternal, hepatitis E, morbidity, mortality, perinatal, pregnancy, viral hepatitis

Abstract

Objective: To evaluate maternal and fetal outcome among pregnant women who have positive serology for hepatitis E IgM. Study Design: Descriptive. Place and duration of study: Department of Obstetrics & Gynaecology, Sir Ganga Ram Hospital over a period of seven years. Methodology: Data of women with clinical presentation of jaundice during pregnancy and who were diagnosed as acute hepatitis E was collected on pre-structured questionnaire after their consent. It was entered in Statistical Package for Social Sciences for analysis. Results: Three hundred and thirty three women had positive serology for hepatitis E IgM. Out of these three hundred were in last trimester of their pregnancy. The gestational age of two hundred and thirty two (77%) women was less than 37 weeks at presentation. Six (2%) pregnancies ended up in miscarriage, fifty four (16 %) had fetal demise in maternal womb while two hundred and seventy three (82%) were viable fetus. One third of live born babies were kept in NICU. Indications of neonatal admission were respiratory distress in 57(72%), jaundice neonatorum in 12(15%), asphyxia neonatorum in 9(12%), while one (1%) had transient tachypnea. Neonates who died in first week of their life were 18(23%).The cause of neonatal death was respiratory distress in 12 (67%) and anoxia in remaining 6 (33%) neonates. Most of the women were discharged home however maternal mortality was recorded in 80(24%) patients, mainly in postpartum period 73(91%). Conclusion: Pregnant women with acute hepatitis E have more complicated course of this viral infection with adverse fetal and maternal implications.

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Published

04/27/2022

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How to Cite

Pregnancy Outcome in Acute Viral Hepatitis E. (2022). Annals of King Edward Medical University, 28(1). https://doi.org/10.21649/akemu.v28i1.5006

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