Unveiling the Renal Symphony: Exploring the Relationship Between Ultrasonographic Parameters and eGFR in Chronic Kidney Disease Patients
DOI:
https://doi.org/10.21649/akemu.v31i1.5715Keywords:
Chronic kidney disease, ultrasonography, cortical thicknessAbstract
Background: Correlation of renal dimensions with renal function in healthy subjects has been firmly established, but which renal dimension correlates best with renal function in chronic kidney disease (CKD) is still debatable. Traditionally, bipolar length of the kidney has been considered a renal function indicator. However, it changes with the size of the body.
Objectives: To determine the correlation between renal ultrasound parameters and eGFR for renal evaluation in patients with CKD.
Methods: This cross-sectional study was undertaken in Pakistan Kidney and Liver Institute Lahore, Radiology department from 5th August 2023 to 4th February 2024. A total of 60 patients of 18-70 years of age with the clinical diagnosis of CKD as mentioned by National Kidney Foundation guidelines (Kidney damage >3 months or decreased GFR (less than 60 mL/min/1.73 m2) for 3 months or more) were included. Patients having a history of renal malignancy or renal surgery, polycystic kidney disease, nephrolithiasis or hydronephrosis or fatty liver disease, on renal replacement therapy, and severe pulmonary, liver, or heart disease were excluded. The ultrasound renal indices like cortical and parenchymal thickness were measured for both kidneys and their respective mean was recorded and analysed.
Results: The correlation between eGFR and renal cortical thickness was moderately significant as evidenced by a p-value of 0.003 and r value of 0.372 (Table III). There was significant moderate correlation with eGFR and renal parenchymal thickness as well (p-value = 0.007, r = 0.346)
Conclusion: The renal parenchymal and cortical thickness correlate positively with eGFR in CKD patients.
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