HISTOPATHOLOGICAL AUDIT OF SALIVARY GLAND NEOPLASMS

Abstract

Abstract:

Background:

Salivary gland neoplasms are uncommon but important presentation to general surgeons.

Objective:

To analyze the relative frequency and distribution of Salivary gland neoplasms in our division.

Setting:

Department of surgery and pathology, Peoples Medical University hospital and GMMMC hospital Sukkur.

Study design:

Descriptive ( case series)

Subjects and methods:

A total of 40 patients registered for salivary gland tumors from oct 2008 to 0ct 2013 were included in the study. A thorough history, clinical examination, routine haematological and biochemical studies were done in all patients. FNAC was done in all cases. All patients were subjected to surgical intervention on standard rules. Each resected specimen was sent for histopathology. Information about age, gender and tumor location was obtained from clinical record and frequency of different neoplasms was studied from histopathological report. All data was collected on especially designed proforma. Data analysis was done using spss version 17.

Results:

A total of 40 patients were registered for salivary gland neoplasms. 28 patients (70%) had parotid lesions, 10 patients (25%) had submandibular gland involvement and 2 patients ( 5%) had minor salivary gland tumors. Patients were between 15 - 80 years of age( mean age =34.7 years).24 patients(60%) were male and 16 (40%) were female,with male to female ratio of 1.5:1.32 . 22 (80%) had benign lesions and 8 patients (20%) had malignant lesions. Pleomorphic adenoma was the most common benign tumor affecting the parotid gland. Adenocarcinoma represented as the most prevelant parotid malignancy. Benign neoplasms occurred in third and fourth decades of life.and malignant neoplasms were diagnosed in sixth and seventh decades of life.

Conclusion:

Salivary gland neoplasms are uncommon but they have occasioned much interest and debate because of broad histological spectrum .The data presented in this study is corroborated with most of the studied literature worldwide.

Keywords:

 Salivary tumors, Parotid tumors, Pleomorphic adenoma, Adenocarcinoma.