Urinary Tract Infections in Children with Nephrotic Syndrome

Abstract

Urinary tract infections are one of the most common infectious complication in children with nephrotic syndrome, particularly during relapses. Infections are recognized as an important cause of morbidity and mortality in children with nephrotic syndrome. This study was conducted to determine the incidence of urinary tract infections in children with nephrotic syndrome and also the organisms causing UTIs. One hundred and thirty five children with the diagnosis of nephrotic syndrome between the ages of 1 to 14 years were analyzed retrospectively. Patients with culture proven urinary tract infections were included in this study. Out of 135 patients 36 (26.6%) were found to have urinary tract infections. This was found to be the major infectious complication in patients. Majority of the infections were caused by gram negative bacilli. E. Coli was the predominant organism 23 patients (63.8%) while other organisms were Klebsiella 6 patients (16.6%), Proteus 11%, Pseudomonas only one patient.