Significance of Histopathological Examination in Hysterectomy Specimens Operated for Clinically Diagnosed Uterine Prolapse

Abstract

Objective: Uterine prolapse is very common gynaecological problem in Pakistan. The uterovaginal prolapse is commonly seen in post menopausal females but in Indo-Pakistan, the prolapse can occur in younger females and multigravida, due to malhandling during deliveries at home by untrained mid wives. Methods: Total 69 cases of clinically diagnosed uterovaginal prolapse specimens were received in the department of pathology, Central Park Medical College, for a period of two years, from August 2017 to August 2019. Results: All 69 cases showed microscopic evidence of prolapse. The commonest age group was between 45 - 64 years, with a mean age of 50.2 years. Chronic non-specific cervicitis was seen in all cases with other incidental lesions in 28 cases (41 %), these were, adenomyosis (13%), leiomyoma (9%), endometrial polyp (7%), chronic endometritis (4.4 %), endocervical polyp (3%), CIN I (3%), tuberculousendometritis (1.6%), while rest of the 41 cases (59%) showed chronic non-specific cervicitis alone. Conclusion: Grossly unremarkable hysterectomies done for uterovaginal prolapse have shown quite a percentage of other incidental lesions, hence proving that all hysterectomy specimens should be evaluated microscopically as well and especially to rule out premalignant and malignant lesions.