Age related histological changes in rat kidney
DOI:
https://doi.org/10.21649/akemu.v10i4.1221Keywords:
Aging. Cell Aging. Lipofuscin. Rats, Inbred F344. Genital Diseases, Female. Kidney. Rats, Wistar. Telomere. Food Deprivation. Glomerular Filtration Rate.Abstract
Histological changes in rat kidney associated with growth and aging were assessed from day one after delivery to thirty months of age. Growth was associated with increase in body and total kidney weight. Different parts of nephron showed an increase in size with growth. In aging rats there was compensatory hypertrophy of renal corpuscle, focal atrophy of proximal and distal convoluted tubules with intra tubular cast and cellular infiltration.
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