Profile of Malignant Tumours of Gastrointestinal Tract at Jinnah Hospital, Lahore

Abstract

A morphological study of malignant tumours of gastrointestinal tract (GIT) was carried out at Department of Pathology, AlIama Iqbal Medical College, Lahore for a period of three years from January 1998 to December 2000. A total of 114 cases of malignant GIT tumours were diagnosed during this period. Out of these 114 malignancies 51(44.74%) were colorectal cancers, 39(34.21%) gastric cancers, 17(14.91%) oesophageal cancers and 7(6.14%) involving the small intestine. Regarding the age incidence of patients with malignant GIT tumours, most of the patients were above the age of 30 years (87.72%) with peak incidence in the age group of 40 to 69 years (57.02%). Sex distribution shows a slight male preponderance, 60 male (52.63%) as compared to 54 women (47.37%). Considering the histological types, out of 51 cases of colorectal malignancies 48 (94.12%) were adenocarcinomas whereas one case(1.47%) each shows morphology of metastatic carcinoma , basaloid carcinoma and Ieiomyosarcoma. In case of gastric tumours, out of 39 malignant cases, 36(92.31%) were adenocarcinomas, two (5.13%) undifferentiated carcinomas while one (2.56%) was diagnosed as squamous cell carcinoma. In case of oesophagus, out of 17 cancers, 12(70.59%) were squamous cell carcinomas and five (29.4 1%), adenocarcinomas. The results were tabulated and compared with similar other studies.