Coagulation Factor V Deficiency: Two Case Reports With a review of Literature.

Abstract

Factor V deficiency is a very rare autosomal recessive trait. Commonest mode of presentation is bleeding from mucous membrane in the form of epistaxis or menorrhagia, later may be so severe as to be life threatening. We received two cases of factor V deficiency at the Pathology Department. of King Edward Medical College, Lahore. One child from paeditric surgery department. and other from Lady Willingdon Hospital, Lahore. Both were investigated, all the tests were normal but prothrombin time and activated partial thromboplastin time was prolonged which was corrected with adsorbed plasma. The diagnosis was confirmed by factor V assay.