Seroprevalance of rubella antibodies among women of reproductive age: A study at Nishtar Hospital Multan

Abstract

Objective: This study was conducted to determine the seroprevalance of rubella antibodies among women of reproductive age and to emphasize the importance of vaccinating this population. Material and methods: Serum specimen of 180 students of College of Nursing Nishtar Hospital Multan was screened with IMMULITE/IMMULITE 1000 Rubella Quantitative IgG assay at MINAR (Multan Institute of Nuclear medicine and Radiotherapy). Results: Out of 180 serum specimens screened 168 (93.33%) were seropositive.9 (5%) were seronegative and 3(1.6%) fell in the intermediate range. All subjects were unmarried, between 16 and 24 years of age and none had a previous history of rubella vaccination. However there was non specific history of fever and rash in 11(6.1%) students. Conclusion: It is evident from this small hospital based study that rubella virus infection is prevalent in our population. However women who reach child bearing age without acquiring natural immunity need to be immunized to prevent repeated pregnancy loss and birth of infants with congenital rubella syndrome. (CRS)