Effects on Contralateral Kidney in Experimental Animal

Abstract

The goal of this experiment was 10 records the degree of hydronephrosis in ligated kidney as well as the changes in contralateral kidney. For this work experimental animal were operated at old PGMI house at Mayo Hospital and ureters were ligated with silk No.3/0. To record the changes in ligated and control kidney, ultrasound machine was used for seven consecutive days. In this work the mean longitudinal length was measured on day 1 upto day 7. The mean difference on the day 1 and 2 was 0.7cm which was statistically insignificant. The mean difference on day and day 3 was 1.1cm, 4 day 1.8cm, 5 day 2.5cm, 6 day 3.2cm and on 7 day was 4.2cm. All these differences shows statistically significant increase in longitudinal length at P<0.0l except on day 3 where the significant was at P<0.05. When day 2 was compared with the rest of seven days the mean difference was significant at P<0.05 and rest of the days the mean difference was significant at P<0.01. On day 3 longitudinal length was significant at P<0.0l, on day 5th and 7h. On day 5e” the mean difference on 5 and 7th day was found statistically significant at P<0.01. After day 6^th the mean difference 1cm was found statistically insignificant. We conclude that the control kidney exhibit significant increase in longitudinal length.